ABCB1 Protein

ATP-Binding Cassette, Sub-Family B, Member 1

Antigen, CD243

CD243 Antigen

MDR1 Protein

Multidrug Resistance Protein 1

P Glycoprotein

PGY 1 Protein

PGY-1 Protein

A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).