Platelet Glycoprotein GPIIb-IIIa Complex


GPIIb IIIa Receptors

GPIIb-IIIa Receptors

Glycoproteins IIb IIIa

Glycoproteins IIb-IIIa

Integrin alpha IIb beta 3

Integrin alpha-IIb beta-3

Integrin alphaIIbbeta3

Platelet Glycoprotein GPIIb IIIa Complex

Receptors, GPIIb-IIIa

alphaIIbbeta3, Integrin

beta-3, Integrin alpha-IIb

Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.