500 kDa HD1 Protein

500-kDa HD1 Protein

HD1 Protein, 500-kDa

HD1, Hemidesmosomal Protein

Hemidesmosomal Protein HD1

A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.