Pregnancy-Associated Plasma Protein-A


IGFBP 4 Metalloproteinase

IGFBP 4 Protease

IGFBP-4 Metalloproteinase

IGFBP-4 Protease

IGFBP-4-Specific Proteinase

Insulin Like Growth Factor Binding Protein 4 Protease

Insulin Like Growth Factor Dependent IGF Binding Protein 4 Protease

Insulin-Like Growth Factor-Dependent IGF Binding Protein-4 Protease

Insulin-Like-Growth Factor Binding Protein-4 Protease

Metalloproteinase, IGFBP-4

PAPP alpha



Pregnancy Associated Plasma Protein A

Pregnancy Associated alpha Plasma Protein

Pregnancy-Associated alpha-Plasma Protein

Protease, IGFBP-4

A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.