Proto-Oncogene Proteins c-kit


Antigens, CD117

CD117 Antigen

CD117 Antigens

Proto Oncogene Protein c kit

Proto Oncogene Protein kit

Proto Oncogene Proteins c kit

Proto-Oncogene Protein c-kit

Proto-Oncogene Protein kit

Proto-Oncogene Protein, kit

Receptor, Stem Cell Factor

SCF Receptor

Stem Cell Factor Receptor

c kit Protein

c kit Receptor

c-kit Protein

c-kit Receptor

c-kit, Proto-Oncogene Protein

c-kit, Proto-Oncogene Proteins

c-kit, p145

kit Proto Oncogene Protein

kit Proto-Oncogene Protein

p145 c kit

p145 c-kit


p145c kit


A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.

See Also