Receptor, IGF Type 1

Synonyms

IGF 1 Receptor

IGF I Receptor

IGF Type 1 Receptor

IGF-1 Receptor

IGF-1 Receptors

IGF-I Receptor

Insulin Like Growth Factor I Receptor

Insulin-Like-Growth Factor I Receptor

Receptor, IGF I

Receptor, IGF Type 1 alpha Subunit

Receptor, IGF Type 1 beta Subunit

Receptor, IGF-1

Receptor, IGF-I

Receptor, Insulin-Like Growth Factor I

Receptor, Insulin-Like Growth Factor Type 1

Receptors, IGF 1

Receptors, IGF-1

Receptors, Insulin-Like-Growth Factor I

A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.