Retinoblastoma-Like Protein p107
Synonyms
RBL1 Protein
Retinoblastoma Like Protein 1
Retinoblastoma Like Protein p107
Retinoblastoma-Like Protein 1
p107 Tumor Suppressor Protein
p107, Retinoblastoma-Like Protein
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.