RGS Protein (G-Protein Signaling)
Regulators of G Protein Signaling Proteins
Regulators of G-Protein Signaling Proteins
A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it to revert to its inactive (GDP-bound) form.