SOX Transcription Factors


SOX Family of Transcription Factors

SOX Transcription Factor Family

SRY (Sex Determining Region Y)-Box Proteins

Transcription Factors, SOX

A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins.