Gamma-Glutamyltransferases, Glutaminyl-Peptide

Glutaminyl Peptide Gamma Glutamyltransferases

Glutaminyl-Peptide Gamma-Glutamyltransferases

Protein Glutamine gamma Glutamyltransferases

Protein-Glutamine gamma-Glutamyltransferases

Protein-glutamine:amine gamma-glutamyltransferase

gamma-Glutamyltransferases, Protein-Glutamine

Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.