Voltage-Gated Sodium Channel beta-1 Subunit


SCN1B Sodium Channel beta Subunit

Voltage Gated Sodium Channel beta 1 Subunit

A voltage-gated sodium channel beta subunit abundantly expressed in SKELETAL MUSCLE; HEART; and BRAIN. It non-covalently associates with voltage-gated alpha subunits. Defects in the SCN1B gene, which codes for this beta subunit, are associated with generalized epilepsy with febrile seizures plus, type 1, and Brugada syndrome 5.