Werner Syndrome Helicase


Helicase, Werner Syndrome

RECQ3 Protein

RECQL2 Protein

Werner Syndrome ATP Dependent Helicase

Werner Syndrome ATP-Dependent Helicase

Werner Syndrome RecQ Like Helicase

Werner Syndrome RecQ-Like Helicase

A DNA-dependent helicase and 3'-5' exonuclease. It has 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS. Mutations in the WRN gene are associated with WERNER SYNDROME.