Zinc Finger E-box-Binding Homeobox 1


NIL 2 A Zinc Finger Protein

NIL-2-A Zinc Finger Protein

TCF8 Protein

Transcription Factor 8

Transcription Factor, Zeb1

Zeb1 Transcription Factor

Zinc Finger E box Binding Homeobox 1

A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.