4-Quinolones

Synonyms

4 Oxoquinolines

4 Quinolinones

4 Quinolones

4-Oxoquinolines

4-Quinolinones

QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.