Autophagy-Related Protein 12


ATG12 Protein

ATG12, Ubiquitin-Like Protein

Autophagy Related Protein 12

Ubiquitin Like Protein ATG12

Ubiquitin-Like Protein ATG12

A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes.