Cytochrome-B(5) Reductase


B5 Reductase, NADH-Cytochrome

Methemoglobin Reductase

Methemoglobin Reductase, NADH

NADH Cytochrome B5 Reductase

NADH Ferrihemoglobin Reductase

NADH Methemoglobin Reductase

NADH-Cytochrome B5 Reductase

NADH-Ferrihemoglobin Reductase

Reductase, Methemoglobin

Reductase, NADH Methemoglobin

Reductase, NADH-Ferrihemoglobin

A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA.