Cytochrome P-450 CYP11B2
Synonyms
Aldosterone Synthase
Aldosterone Synthase Cytochrome P-450
Aldosynthase
CYP 11B2
CYP11B2
Cytochrome P 450 CYP11B2
Cytochrome P 450c11AS
Cytochrome P-450c11AS
Cytochrome P450 11B2
Cytochrome P450Aldo
P450c11AS
Steroid 18 Hydroxylase
Steroid 18-Hydroxylase
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.