DNA Restriction-Modification Enzymes
DNA Restriction Modification Enzymes
Enzymes, DNA Restriction-Modification
Modification Systems, Restriction
Restriction Modification Systems
Restriction-Modification Enzymes, DNA
Systems, Restriction Modification
Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.