Forkhead Box Protein O3


FOXO3 Protein

Forkhead in Rhabdomyosarcoma Like 1 Protein

Forkhead in Rhabdomyosarcoma-Like 1 Protein

Protein, FOXO3

A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.