Giant Cells, Langhans


Cells, Langhans Giant

Cells, Langhans-Type Giant

Giant Cells, Langhans-Type

Langhans Giant Cells

Langhans Type Giant Cells

Langhans-Type Giant Cells

Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.