Hemoglobin, Sickle

Synonyms

Deoxygenated Sickle Hemoglobin

Deoxyhemoglobin S

Hemoglobin S

Hemoglobin SS

Hemoglobin, Deoxygenated Sickle

SS, Hemoglobin

Sickle Hemoglobin

Sickle Hemoglobin, Deoxygenated

An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.