Leukocyte L1 Antigen Complex
Synonyms
27E10 Antigen
Antigen L1, Myelomonocytic
Antigen, 27E10
Antigen, L1
Calcium Binding Myeloid Protein P8,14
Calcium-Binding Myeloid Protein P8,14
Calgranulin
Calprotectin
L1 Antigen
L1 Protein, Leukocyte
Leukocyte L1 Protein
Migratory Inhibitory Factor Related Protein MRP
Migratory Inhibitory Factor-Related Protein MRP
Myelomonocytic Antigen L1
A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.