Lymphocyte Culture Test, Mixed

Synonyms

Leukocyte Culture Test, Mixed

Leukocyte Reaction, Mixed

Leukocyte Reactions, Mixed

Lymphocyte Reaction, Mixed

Lymphocyte Reactions, Mixed

Mixed Leukocyte Culture Test

Mixed Leukocyte Reaction

Mixed Leukocyte Reactions

Mixed Lymphocyte Culture Test

Mixed Lymphocyte Reaction

Mixed Lymphocyte Reactions

Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.