Mutagenesis, Insertional


Activation, Insertional

Activations, Insertional

Cassette Mutagenesis

Gene Insertion

Gene Insertions

Insertion Mutation

Insertion Mutations

Insertion, Gene

Insertion, Sequence

Insertional Activation

Insertional Activations

Insertional Mutagenesis

Insertional Mutagenesis, Viral

Insertions, Gene

Insertions, Sequence

Linker Insertion Mutagenesis

Linker-Insertion Mutagenesis

Mutagenesis, Cassette

Mutagenesis, Linker-Insertion

Mutagenesis, Viral Insertional

Mutation, Insertion

Mutations, Insertion

Sequence Insertion

Sequence Insertions

Viral Insertional Mutagenesis

Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.