Myasthenia Gravis, Neonatal


Antenatal Myasthenia Gravis

Myasthenia Gravis, Antenatal

Myasthenia Gravis, Neonatal, Persistent

Myasthenia Gravis, Neonatal, Transient

Myasthenia Gravis, Persistent, Neonatal

Myasthenia Gravis, Transient, Neonatal

Neonatal Myasthenia Gravis

Neonatal Myasthenia Gravis, Persistent

Neonatal Myasthenia Gravis, Transient

Persistent Neonatal Myasthenia Gravis

Transient Neonatal Myasthenia Gravis

A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)