Nogo Proteins


NI 220 Protein

NI 250 Protein

NI 35 250

NI 35 Protein

NI-220 Protein

NI-250 Protein

NI-35 Protein


Neurite Growth Inhibitor 35 350

Neurite Growth Inhibitor 35-350

Nogo 66 Protein

Nogo A Protein

Nogo B Protein

Nogo C Protein

Nogo Protein

Nogo-66 Protein

Nogo-A Protein

Nogo-B Protein

Nogo-C Protein

Reticulon 4 B Protein

Reticulon 4 Protein

Reticulon 4-B Protein

Reticulon-4 Protein

Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system.