Nucleic Acid Denaturation


Acid Denaturation, Nucleic

DNA Denaturation

DNA Melting

Denaturation, DNA

Denaturation, Nucleic Acid

Denaturation, RNA

Nucleic Acid Denaturations

RNA Denaturation

Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.