Pyrroline Carboxylate Reductases
Carboxylate Reductases, Pyrroline
Reductases, Pyrroline Carboxylate
A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 220.127.116.11) and the 5-oxidoreductase (EC 18.104.22.168). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.