Rhodamine 123
Synonyms
Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
A fluorescent probe with low toxicity which is a potent substrate for P-glycoprotein and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of P-glycoprotein in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)
See Also