RNA 5' Terminal Oligopyrimidine Sequence

Synonyms

5' TOP Messenger RNA

5' TOP Sequence

5' TOP Sequences

5' TOP mRNA

RNA 5' Terminal Oligopyrimidine Regulatory Sequence

Sequence, 5' TOP

Sequences, 5' TOP

A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.