Type VII Secretion Systems


ESX Secretion Systems

Secretion System, T7SS

Secretion Systems, ESX

Secretion Systems, Type 7

Secretion Systems, Type VII

System, T7SS Secretion

Systems, ESX Secretion

T7SS Secretion System

Type 7 Secretion Systems

Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These are also known as ESX secretion systems because the first to be discovered is involved in secreting major virulence factors EsxA and EsxB. There are several subtypes of T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes share some core components including an inner membrane channel-forming ATPase complex, a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing membrane.