Zinc Fingers


Finger, Zinc

Fingers, Zinc

Motif, Zinc Finger

Motifs, Zinc Finger

Zinc Finger

Zinc Finger Motif

Zinc Finger Motifs

Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.