1-Alkyl-2-acetylglycerophosphocholine Esterase
Synonyms
1 Alkyl 2 acetylglycerophosphocholine Esterase
2-Acetylhydrolase, PAF
Acetylhydrolase II, PAF
Acetylhydrolase, PAF
Esterase, 1-Alkyl-2-acetylglycerophosphocholine
Factor Hydrolase, Platelet-Activating
Hydrolase, Platelet-Activating Factor
Lipoprotein Associated Phospholipase A2
Lipoprotein-Associated Phospholipase A(2)
Lipoprotein-Associated Phospholipase A2
Lp PLA2
Lp-PLA(2)
Lp-PLA2
PAF 2 Acetylhydrolase
PAF 2 Acylhydrolase
PAF 2-Acetylhydrolase
PAF 2-Acylhydrolase
PAF Acetylhydrolase
PAF Acetylhydrolase II
Phospholipase A2, Lipoprotein-Associated
Platelet Activating Factor Hydrolase
Platelet activating Factor Acetylhydrolase IB
Platelet-Activating Factor Hydrolase
Platelet-activating Factor Acetylhydrolase IB
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.