1-Alkyl-2-acetylglycerophosphocholine Esterase

Synonyms

1 Alkyl 2 acetylglycerophosphocholine Esterase

2-Acetylhydrolase, PAF

Acetylhydrolase II, PAF

Acetylhydrolase, PAF

Esterase, 1-Alkyl-2-acetylglycerophosphocholine

Factor Hydrolase, Platelet-Activating

Hydrolase, Platelet-Activating Factor

Lipoprotein Associated Phospholipase A2

Lipoprotein-Associated Phospholipase A(2)

Lipoprotein-Associated Phospholipase A2

Lp PLA2

Lp-PLA(2)

Lp-PLA2

PAF 2 Acetylhydrolase

PAF 2 Acylhydrolase

PAF 2-Acetylhydrolase

PAF 2-Acylhydrolase

PAF Acetylhydrolase

PAF Acetylhydrolase II

Phospholipase A2, Lipoprotein-Associated

Platelet Activating Factor Hydrolase

Platelet activating Factor Acetylhydrolase IB

Platelet-Activating Factor Hydrolase

Platelet-activating Factor Acetylhydrolase IB

A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.