Cholesterol Side-Chain Cleavage Enzyme


20,22 Desmolase


CYP 11A1


Cholesterol Desmolase

Cholesterol Monooxygenase (Side-Chain-Cleaving)

Cholesterol Side Chain Cleavage Enzyme

Cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)

Cytochrome P 450 CYP11A1

Cytochrome P-450 CYP11A1

Cytochrome P-450(scc)

Cytochrome P450 11A1

Cytochrome P450scc

A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.