Cytochrome P-450 CYP2C8
Synonyms
4-Hydroxylase, S-Mephenytoin
CYP2C8
CYP2C8, Cytochrome P-450
CYPIIC8
Cytochrome P 450 CYP2C8
Cytochrome P450 MP 20
Cytochrome P450 MP-20
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8
P-450 CYP2C8, Cytochrome
P450 MP-20, Cytochrome
S Mephenytoin 4 Hydroxylase
S-Mephenytoin 4-Hydroxylase
A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE