Receptor, Insulin

Synonyms

Insulin Receptor

Insulin Receptor Protein Tyrosine Kinase

Insulin Receptor Protein-Tyrosine Kinase

Insulin Receptor alpha Chain

Insulin Receptor alpha Subunit

Insulin Receptor beta Chain

Insulin Receptor beta Subunit

Insulin Receptors

Insulin-Dependent Tyrosine Protein Kinase

Receptors, Insulin

A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.