Tartrate-Resistant Acid Phosphatase


AcPase V

Acid Phosphatase V

Acid Phosphatase, Tartrate-Resistant

Phosphatase V, Acid

Phosphatase, Tartrate-Resistant Acid

TRAP Type 5 AcPase


Tartrate Resistant Acid Phosphatase

Tartrate Resistant Acid Phosphatase Type 5

Tartrate-Resistant Acid Phosphatase Type 5

Type 5 Acid Phosphatase


V, AcPase

V, Acid Phosphatase

One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.