Vascular Endothelial Growth Factor A



Glioma Derived Vascular Endothelial Cell Growth Factor

Glioma-Derived Vascular Endothelial Cell Growth Factor

Permeability Factor, Vascular



Vascular Endothelial Growth Factor

Vascular Endothelial Growth Factor-A

Vascular Permeability Factor


The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.