Gastrin Producing Tumor

Gastrin-Producing Tumor

Gastrin-Producing Tumors


Islet Cell Tumor, Ulcerogenic

Tumor, Gastrin-Producing

Tumors, Gastrin-Producing

Ulcerogenic Islet Cell Tumor

A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).