Steroid 21-Hydroxylase


21 Hydroxylase


Cytochrome P 450 21 Hydroxylase

Cytochrome P 450 CYP21

Cytochrome P 450 c21

Cytochrome P-450 21-Hydroxylase

Cytochrome P-450 CYP21

Cytochrome P-450 c21

Cytochrome P-450(c-21)

Cytochrome P450c21

P-450 c21, Cytochrome

Progesterone 21 Hydroxylase

Progesterone 21-Hydroxylase

Steroid 21 Hydroxylase

Steroid 21 Monooxygenase

Steroid 21-Monooxygenase

Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)


An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).