25-Hydroxyvitamin D3 1-alpha-Hydroxylase


1-alpha-Hydroxylase, 25-Hydroxyergocalciferol

1-alpha-Hydroxylase, 25-Hydroxyvitamin D

1-hydroxylase, 25-Hydroxyvitamin D2

25 Hydroxycholecalciferol 1 Hydroxylase

25 Hydroxyergocalciferol 1 alpha Hydroxylase

25 Hydroxyvitamin D 1 alpha Hydroxylase

25 Hydroxyvitamin D2 1 hydroxylase

25 Hydroxyvitamin D3 1 alpha Hydroxylase

25-Hydroxycholecalciferol 1-Hydroxylase


25-Hydroxyergocalciferol 1-alpha-Hydroxylase

25-Hydroxyvitamin D 1-alpha-Hydroxylase

25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase

25-Hydroxyvitamin D2 1-hydroxylase


Calcidiol 1 Monooxygenase

Calcidiol 1-Monooxygenase

Calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)

Cytochrome P 450 CYP27B1

Cytochrome P-450 CYP27B1

A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol).