Motor Neuron Disease


Anterior Horn Cell Disease

Familial Motor Neuron Disease

Lateral Scleroses

Lateral Scleroses, Primary

Lateral Sclerosis

Lateral Sclerosis, Primary

Lower Motor Neuron Disease

Motor Neuron Disease, Familial

Motor Neuron Disease, Lower

Motor Neuron Disease, Secondary

Motor Neuron Disease, Upper

Motor Neuron Diseases

Motor System Disease

Motor System Diseases

Neuron Disease, Motor

Neuron Diseases, Motor

Primary Lateral Scleroses

Primary Lateral Sclerosis

Scleroses, Lateral

Scleroses, Primary Lateral

Sclerosis, Lateral

Sclerosis, Primary Lateral

Secondary Motor Neuron Disease

Upper Motor Neuron Disease

Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)