Prader-Willi Syndrome


Labhart Willi Prader Fanconi Syndrome

Labhart Willi Syndrome

Labhart-Willi Syndrome

Labhart-Willi-Prader-Fanconi Syndrome

Prader Labhart Willi Syndrome

Prader Willi Syndrome

Prader-Labhart-Willi Syndrome

Royer Syndrome

Royer's Syndrome

Royers Syndrome

Syndrome, Labhart-Willi

Syndrome, Labhart-Willi-Prader-Fanconi

Syndrome, Prader-Labhart-Willi

Syndrome, Prader-Willi

Syndrome, Royer

Syndrome, Royer's

Syndrome, Willi-Prader

Willi Prader Syndrome

Willi-Prader Syndrome

An autosomal dominant disorder caused by deletion of the proximal long arm of the paternal chromosome 15 (15q11-q13) or by inheritance of both of the pair of chromosomes 15 from the mother (UNIPARENTAL DISOMY) which are imprinted (GENETIC IMPRINTING) and hence silenced. Clinical manifestations include MENTAL RETARDATION; MUSCULAR HYPOTONIA; HYPERPHAGIA; OBESITY; short stature; HYPOGONADISM; STRABISMUS; and HYPERSOMNOLENCE. (Menkes, Textbook of Child Neurology, 5th ed, p229)